Here’s an simplified example of the steps I take to create one of my Steampunk Monkey Nation characters. I scan my pencil sketch and open in Painter. It’s used as a guide for creating the black and white line work with Painter’s Scratchboard tool. Color is applied to a lower layer which shows through the line work since it’s converted to a “Gel” composite layer (something similar to Photoshop’s Darken or Multiply layer attribute.)
Here’s a bit of background on Professor Horatio Sprocketnotch:
Scientist
Brilliant but quite mad mastermind behind of scores of scientific breakthroughs. These include: the creation of the Eye of Radical Hyperbaric Transcendence and Licorice Legs. Pictured holding his greatest creation, the inter-dimensional tsunami egg of destruction, which worked perfectly the first and only time it was activated.